The following players made their major league debuts as Minnesota Twins on May 24.
Cole De Vries (P) – May 24, 2012 – Signed by the Minnesota Twins as an amateur free agent on August 22, 2006. Cole, a Minnesota native was saddled with he loss during his big league debut.
Matt Macri (3B) – May 24, 2008 – Traded by the Colorado Rockies to the Minnesota Twins for Ramon Ortiz on August 15, 2007. Matt made his big league debut in a 19-3 loss to the Detroit Tigers in Comerica Park but he did pretty well for himself going 2 for 3 with a run scored, a RBI and a stolen base.