October 6, 1965 – The Twins play their first World Series game at Metropolitan Stadium with 47,797 fans in the stands against the Los Angeles Dodgers and win the game 8-2 behind the complete game pitching of Mudcat Grant. Grant becomes the first African-American to win a World Series game. In the third inning the Twins scored six times and rookie second baseman Frank Quilici had a double and a single in the same inning in his first World Series game. Don Drysdale took the defeat. Don Mincher and Zoilo Versalles hit round trippers. Sandy Koufax (26-8) refuses to pitch the first game of the World Series against the Twins because game is scheduled on Yom Kippur, the most sacred of the Jewish holidays. Tony Oliva tied a World Series record for most putouts in a nine-inning game in right field (7). Box score
Hubert Humphrey, Vice-President of the United States, and a former mayor of Minneapolis threw out the ceremonial first pitch.